Natural Solutions|April 2020
Interest in brain health has been on the rise in recent years as both the prevalence and awareness of neurocognitive disorders like Alzheimer’s Disease have increased. According to the Alzheimer’s Association, 10 percent of Americans age 65 or older (5.6 million people) have Alzheimer’s Disease. Equally if not more alarming, that percentage increases significantly with age. It is estimated that nearly a third (32 percent) of individuals 85 or older is living with Alzheimer’s.

As such figures indicate, most of us are sadly familiar with neurocognitive disorders like Alzheimer’s Disease. Chances are high that someone in your family is afflicted, or a close friend’s family. And like most health-oriented consumers, there’s a good chance that you’re interested in improving brain health.

For the average adult, brain development peaks at age 25, and after age 40 brain volume begins to decrease at a rate of five percent per decade. Neurons and their connecting pathways start shrinking, and after age 70 the rate of decline increases even further. It’s no wonder that older consumers are interested in maintaining brain health to stave off declining cognitive function. Last year AARP conducted an on-line survey of nearly 2,300 participants and found that more than one-third of adults age 74 or older was taking a supplement for brain health. But it is not just older consumers who are concerned about brain health. Millennials, too, are gravitating to products that help promote greater mental focus and acuity and reverse the effects of aging.

Nutritional supplement sales reflect a growing appetite for products aimed at improving cognitive function. It’s estimated that the global brain health supplements market will reach $11.6 billion by 2024, a nearly five-fold increase compared to the $2.3 billion in sales from 2015. Consumers face an array of supplements that promote brain health, but it’s important to consider efficacy and safety, as demonstrated by research and clinical studies.

Mind Your P’s and Q’s

An extensive list of clinical studies highlights a link between brain health and other benefits with a naturally occurring antioxidant ingredient called pyrroloquinoline quinone, or PQQ. The ingredient is found in trace amounts in vegetables, fruits, meat, and in human breast milk, and it has been commercialized as a nutraceutical. Research suggests that the PQQ compound may play a role in preserving and improving cognitive function, in both humans and animals and delay aging. Some early findings show that it may also support heart health, reduce stress and improve sleep.

A natural source of PQQ was developed by Mitsubishi Gas Chemical Co., Inc. in Japan under the brand name BioPQQ® in the United States, Canada and Japan. While other forms of PQQ are available on the market, the vast majority of scientific research has been developed on BioPQQ specifically.

BioPQQ has significantly higher antioxidant properties than Vitamin C and E, and as an antioxidant ingredient it has been shown to remove active oxygen radicals that are often linked to “oxidative stress” which can contribute to neurodegenerative diseases that include Alzheimer’s and other dementias. In this way, PQQ may protect neurons in the brain that are susceptible to cell damage.

Mighty Mitochondria


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April 2020