Try GOLD - Free
Treatment slows fatal Huntington's
The Chronicle
|September 25, 2025
SCIENTISTS have slowed the progression of Huntington’s disease for the first time with a “groundbreaking” new treatment.
-
Experts from University College London (UCL) said the finding could “change everything” for patients with the condition, which gets worse over time and has no cure.
The disease affects movement, thinking and mood.
The study tested a new gene therapy, AMT-130, which is delivered by brain surgery.
The early stage clinical trials among 29 patients concluded that those who were given a high dose of the treatment experienced 75% less disease progression after 36 months, according to uniQure, a gene therapy company based in the Netherlands and the US. A single dose is expected to last for a person's life.
"This result changes everything," said principal investigator Professor Ed Wild, from the UCL Huntington's Disease Centre.
This story is from the September 25, 2025 edition of The Chronicle.
Subscribe to Magzter GOLD to access thousands of curated premium stories, and 10,000+ magazines and newspapers.
Already a subscriber? Sign In
MORE STORIES FROM The Chronicle
The Chronicle
Bruno is top of Keegan's wish list
FORMER Newcastle United manager Kevin Keegan has admitted if he returned to management the one player he would love to sign is Magpies captain Bruno Guimaraes.
1 mins
December 13, 2025
The Chronicle
Young adult unemployment has soared in the UK since Labour came to power
THE number of young people claiming unemployment benefits has soared across most of the UK since Labour came to power - even as the overall number of claimants has fallen.
3 mins
December 13, 2025
The Chronicle
Youngsters ease past Forest into next round
ACADEMY manager Robin Nicholls has discussed the importance of the FA Youth Cup at Sunderland and the valuable development opportunities it provides.
1 mins
December 13, 2025
The Chronicle
'Game-changing' buggy for Kinsley
MEET six-year-old Kinsley Ridley from North Tyneside, who has Dandy Walker malformation and development delay.
2 mins
December 13, 2025
The Chronicle
It's sad that friendships fall out...
Daniel Radcliffe, Jonathan Groff, and Lindsay Mendez discuss friendship and loss in their roles in a new filmed stage version of Stephen Sondheim's musical Merrily We Roll Along. By LYNN RUSK
4 mins
December 13, 2025
The Chronicle
Gateshead triathlete Kate wins world title in Qatar
KATE WAUGH defied her own doubts to cap a ‘dream’ season with the T100 Triathlon world title.
2 mins
December 13, 2025
The Chronicle
Why was it built in the first place, asks council leader
A YEAR on from the closure of the Gateshead Flyover, council leader Martin Gannon is plagued by the question: 'Why the hell did they build it in the first place?'
2 mins
December 13, 2025
The Chronicle
Twelve months on, abandoned eyesore flyover is still standing
AN ABANDONED and crumbling eyesore running through the heart of Tyneside, the Gateshead Flyover has now stood empty for a full year.
3 mins
December 13, 2025
The Chronicle
Council warns it must find £8m of extra savings
A North East council has warned that it will need to make £8 million worth of extra cuts next year after a Government funding shakeup.
2 mins
December 13, 2025
The Chronicle
Former Newcastle keeper Krul has sympathy
FORMER Newcastle United star Tim Krul has opened up on the difficulties of being a second choice goalkeeper amid the battle for the gloves at St James’ Park between Nick Pope and Aaron Ramsdale.
1 mins
December 13, 2025
Listen
Translate
Change font size