Burn fat & beat diabetes

There's now proof GLP-1 meds can prevent or reverse blood sugar issues for up to 99% of prediabetics

- by ALLISON NEMETZ

An astonishing fact about new meds helping millions lose weight: A study in the New England Journal of Medicine found tirzepatide, the active ingredient in Mounjaro and Zepbound, can prevent nearly all high-risk patients from developing diabetes, beating a placebo by 10 times. "I spoke at the European Association for the Study of Diabetes, and I joked they'll have to switch to 'Study of Prediabetes,'" says Louis J. Aronne, M.D., part of the research team. "There's not gonna be many people with diabetes left." Keep reading for the latest on these life-changing, lifesaving treatments.

Mounjaro and Zepbound along with Ozempic and Wegovy are part of a new wave of prescription injectable diabetes and obesity medications that mimic the hormone GLP-1, keeping levels up to 1,000 times higher than normal. This leads to radically reduced hunger and improved blood sugar control, says Dr. Aronne, director of the Comprehensive Weight Control Center at Weill Cornell Medicine. Among many benefits, rapid weight loss gets virtually all the hype. That may soon change.

Laurie shed 55 lbs

How did Laurie's appetite change on Zepbound? "I started at 2.5 mg, and I still felt it immediately," she says. While she was expecting less hunger, she was surprised to find her tastes changed for the better too. "I was never a big drinker, but I stopped wanting alcohol at all," she shares. And while she still has a sweet tooth, "I'm happy with a Yasso bar. I don't 'need' premium ice cream anymore." Laurie, who was gradually moved up to a 15-mg dose, is no longer pre-diabetic or inflamed and is down five sizes.

It's about so much more than numbers on the scale