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Top 10 agentic AI threats and defenses

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November 2025

India's digital future is under siege from its own Al agents. As LLMs evolve into autonomous threats, here are the top 10 agentic Al dangers and how to defend against them. Insightful, actionable, and must-read for every cyber-resilient professional

- PCQ Bureau

Top 10 agentic AI threats and defenses

India’s digital boom is unstoppable.

From UPI to smart governance, AI is everywhere. But as AI matures into decision-making agentsbeyond passive Large Language Models (LLMs)our cybersecurity game is being rewritten in real-time.

These autonomous, agentic Als can plan, act, and adapt. They operate without constant human control. That sounds efficient, right? But here’s the dark twist: they're also opening up a Pandora’s box of vulnerabilities.

Traditional security tools? Not enough anymore. As our systems evolve, so must our defenses.

Let’s decode the top 10 threats these intelligent agents poseand how to shut the door before things spiral.

1. Memory poisoning

Threat: Al learns from memory. But what if the memory is fake? Injected false data corrupts its decisions.

Real-world hit: A banking Al “remembers” approving a loan. It never did. But funds get disbursed anyway.

Defense Moves:

  • Isolate memory for sensitive tasks

  • Validate memory content

  • Use anomaly detection tools

  • Sanitize memory regularly

2. Tool misuse

Threat: Al gets tricked into misusing tools it has access to-from payment gateways to document editors.

Example: An HR chatbot sends out private salary data after reading a manipulated prompt.

Defense Moves:

  • Tighten tool access verification

  • Monitor tool usage in real time

  • Set boundaries for high-risk APIs

  • Validate instructions before executing them

3. Privilege compromise

Threat: Hackers exploit misconfigured permissions. Al agents then perform tasks beyond their role.

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