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Scientists Revive Extinct Dire Wolf After 13,000 Years: Genetic Breakthrough by Colossal Biosciences

Scientific India

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March-April 2025

How ancient dire wolf DNA extracted from fossilised remains - is too degraded and damaged to biologically copy or clone-Paleogeneticist Dr Nic Rawlence, Otago University

Scientists Revive Extinct Dire Wolf After 13,000 Years: Genetic Breakthrough by Colossal Biosciences

The dire wolf has been extinct for over 10,000 years. These two wolves were brought back from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed by Colossal from ancient DNA found in fossils dating back 11,500 and 72,000 years. This moment marks not only a milestone for us as a company but also a leap forward for science, conservation, and humanity. From the beginning, our goal has been clear: To revolutionize history and be the first company to use CRISPR technology successfully in the de-extinction of previously lost species.

The Genesis of the Project

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