1. Increase in hat and shoe size over time. A tumor of pituitary gland of brain producing excess growth hormone causes a condition known as acromegaly, which can result in increasing head and feet size.
2. Milk production from breasts (in a woman who is neither breastfeeding nor pregnant)This condition is called galactorrhea and is caused by a tumor of pituitary gland, that produces excess prolactin hormone. In addition to milk discharge from nipples, these women can also have amenorrhea (absence of or irregular periods).
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