Cancer poses a significant challenge for the pharmaceutical industry, driving a constant search for improved oncology drugs. The industry has now put the spotlight on antibodydrug conjugates (ADCs), representing a promising frontier in targeted cancer treatment. 2023 was a big year for ADCs, marked by a total of 76 deals (by December 26, 2023) encompassing licensing agreements, collaborations, and acquisitions. Majority of the big pharma companies have either announced acquisitions or partnership with smaller biotech companies in this space, the latest entrant is Johnson & Johnson (J&J) which on January 8, 2024, made a significant move with a $2 billion acquisition of ADC developer Ambrx Biopharma, bolstering its ADC pipeline. Just a few weeks back, on December 26, 2023, J&J sealed a substantial $1.7 billion deal with South Korea's LegoChem Biosciences for the development and commercialisation of LCB84, a promising Trop2-directed ADC. The preclinical data for LCB84 highlighted a distinct safety and efficacy profile across various cancers, underlining the significance of these strategic advancements in the ADC landscape.
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Esta historia es de la edición BioSpectrum Asia Feb 2024 de BioSpectrum Asia.
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