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At-home saliva test for prostate cancer 'better than blood test'

April 10, 2025

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The Guardian

An at-home spit test appears to perform better at predicting prostate cancer risk than the current frontline test, a study suggests.

- Hannah Devlin

The test assesses 130 genetic variants to provide a risk score for prostate cancer, the second most common cause of cancer deaths in men in the UK.

This so-called polygenic risk score was found to be a more powerful predictor of aggressive prostate cancer than the standard blood test used in the NHS which measures a protein, prostate-specific antigen (PSA).

Prof Ros Eeles, who led the study at the Institute of Cancer Research, London, said: "With this test, it could be possible to turn the tide on prostate cancer."

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