ESTROGEN COULD AID IN THERAPIES FOR PROGRESSIVE MULTIPLE SCLEROSIS

About 100,000 of the estimated million persons in the United States with multiple sclerosis (MS) have a progressive form of the disease, with symptoms worsening over time or following periods of remission.

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"Progressive MS is profoundly challenging because it is relentless and treatment options are limited," said Francisco P. Gomez, a neurologist who specializes in MS and neuroimmunology.

MS is believed to occur when the immune system attacks the myelin sheath -- the protective coating of the nerve fibers that transmit electrical impulses throughout the body -- and disrupt this communication. The disease occurs more often in women, older people and those in northern latitudes.

Symptoms include fatigue, numbness or tingling, bladder and bowel problems and cognitive issues, but difficulty walking and balancing are the most common symptoms -- and these are more pronounced in the progressive form of the disease. In addition, the progressive form is more prevalent among Black patients.