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Eli Lilly daily weight-loss pill shows benefits in clinical trial

The Guardian

|

April 18, 2025

A significant trial of a daily weight-loss pill has found that it helped people to shed the pounds and reduce their blood sugar levels, making it a contender to join the new wave of drugs that combat obesity and diabetes.

- Ian Sample

People who took a 36mg pill of orforglipron lost an average of 7.3kg (16lbs) over nine months, according to results from a phase 3 clinical trial reported by the drug's manufacturer, Eli Lilly, yesterday. The trial, which enrolled 559 obese people with type 2 diabetes from the US, China, India, Japan and Mexico, found that the daily pill reduced blood sugar levels, in some cases bringing them below the formal threshold for diabetes.

Results have been eagerly awaited by researchers because orforglipron is the first daily pill version of a GLP-1 agonist, used in weight-loss injections such as Ozempic and Wegovy.

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time to read

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time to read

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time to read

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Stark warning for Starmer after election rout in Wales

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time to read

4 mins

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time to read

2 mins

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time to read

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time to read

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The Guardian

Bacon should be sold with bowel cancer warning, say scientists

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time to read

1 mins

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The Guardian

Inaccessible chargers 'stopping disabled drivers going electric'

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time to read

1 mins

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