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Cannabis use for pain or depression 'adds to risk of paranoia'

The Guardian

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August 27, 2025

People who start smoking cannabis to combat pain, anxiety or depression are at a higher risk of developing paranoia than those who use the drug recreationally, a study has found.

- Tobi Thomas

Cannabis use for pain or depression 'adds to risk of paranoia'

Researchers analysed answers from 3,389 former and current cannabis users aged over 18 who took part in the Cannabis&Me survey and had no clinical history of psychosis.

Published in the British Medical Journal and led by academics at King's College London, the research found that those who started using cannabis to self-medicate for a condition such as pain, anxiety or depression, and if they were experiencing minor psychotic symptoms, had higher paranoia scores, while those with the lowest scores said they had used cannabis for fun or because they were curious.

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