![PIERCING CANCER'S INNER SANCTUM](https://cdn.magzter.com/1430147033/1700746159/articles/XMC-LITLT1700818386626/PIERCING-CANCERS-INNER-SANCTUM.jpg)
SASCHA ROTH FIGURED THAT WHEN have cancer in your colon and lymph nodes and your oncologist calls you after business hours, two days before you're scheduled to begin a brutal five-week course of radiation therapy, it's probably not good news-especially when the first thing she says is, "Are you sitting down?"
Roth was the first patient that enrolled into a clinical trial to test a new immunotherapy drug, designed to unleash the body's natural immune response on the tumor cells, on patients with early stage cancers. The results were miraculous: One hundred percent of the patients went into total remission-perhaps the first time that's ever happened in any cancer clinical trial, according to Luis Diaz, head of the division of solid tumor oncology in Memorial Sloan Kettering's Department of Medicine and a designer of the trial. The trial suggested the new therapies, if delivered early enough, might not only obviate the need for traditional therapies notorious for their brutal side effects, like chemo, radiation and surgery. They could potentially cure the disease altogether.
Roth's doctor was jubilant: "We've reviewed all your scans, biopsies-everything," she says the doctor told her. "There is zero sign of cancer. We can't radiate you knowing there's no cancer in your body."
The trial, published last year in The New England Journal of Medicine, electrified the field of cancer research and held out the promise of a powerful new approach that might help relieve many people from the suffering and anxiety caused by a scourge that kills 610,000 people each year in the U.S.
Bu hikaye Newsweek Europe dergisinin December 01 - 08, 2023 (Double Issue) sayısından alınmıştır.
Start your 7-day Magzter GOLD free trial to access thousands of curated premium stories, and 8,500+ magazines and newspapers.
Already a subscriber ? Giriş Yap
Bu hikaye Newsweek Europe dergisinin December 01 - 08, 2023 (Double Issue) sayısından alınmıştır.
Start your 7-day Magzter GOLD free trial to access thousands of curated premium stories, and 8,500+ magazines and newspapers.
Already a subscriber? Giriş Yap
![The Fight To Ban Child Marriage](https://reseuro.magzter.com/100x125/articles/9708/1731957/Bn6wwccTp1718362066129/crp_THE-FIGHT-TO-BAN-CHILD-MARRIAGE.jpg)
The Fight To Ban Child Marriage
Under-18s can legally wed in most U.S. states but young spouses are often left physically, emotionally and economically vulnerable, campaigners say
![Major League Error](https://reseuro.magzter.com/100x125/articles/9708/1731957/l9PbkYmR51718363275700/MAJOR-LEAGUE-ERROR.jpg)
Major League Error
Why baseball fans have long thought Ty Cobb to be a racist when he wasn't
![The TikTok Election](https://reseuro.magzter.com/100x125/articles/9708/1731957/GkoGFXO5C1718362867813/THE-TIKTOK-ELECTION.jpg)
The TikTok Election
With both Donald Trump and Joe Biden now on the app, could it help determine the next U.S. president in November?
![Failure to Deliver](https://reseuro.magzter.com/100x125/articles/9708/1731957/xQ7JRVNRL1718362474668/FAILURE-TO-DELIVER.jpg)
Failure to Deliver
Multinational companies embraced Chinese factories to lower costs. Their excessive reliance ended up being a central cause of the COVID supply chain meltdown
![BEST SPECIALISTS & SURGEONS](https://reseuro.magzter.com/100x125/articles/9708/1731957/k5h3ak1a-1718361137636/BEST-SPECIALISTS-SURGEONS.jpg)
BEST SPECIALISTS & SURGEONS
FINDING THE BEST MEDICAL SPECIALIST IS A DAUNTING TASK for anyone requiring specific treatment.
![SURGEONS MAGIC TOUCH](https://reseuro.magzter.com/100x125/articles/9708/1731957/jf6JhFHJw1718359763107/SURGEONS-MAGIC-TOUCH.jpg)
SURGEONS MAGIC TOUCH
Americans turn down syringes but go UNDER SCALPELS. What do these doctors know that the rest of medicine doesn't?
![ARABIAIAN MIGHT](https://reseuro.magzter.com/100x125/articles/9708/1724327/4_74oo9zN1717698801749/ARABIAIAN-MIGHT.jpg)
ARABIAIAN MIGHT
SAUDI ARABIA'S INCREASING STRENGTH MEANS IT NOW HAS MUCH MORE CLOUT WITH ITS PARTNERS, INCLUDING THE U.S.
![Bringing Trump's Trial to Life](https://reseuro.magzter.com/100x125/articles/9708/1724327/w4Y7L6jEy1717698240148/BRINGING-TRUMPS-TRIAL-TO-LIFE.jpg)
Bringing Trump's Trial to Life
Sketch artist Isabelle Brourman tells Newsweek what it was like covering the former president’s court case
![Iran Examines the Nuclear Option](https://reseuro.magzter.com/100x125/articles/9708/1724327/wZ6f99fHM1717697070537/IRAN-EXAMINES-THE-NUCLEAR-OPTION.jpg)
Iran Examines the Nuclear Option
Tehran’s rhetoric could spark an arms race in the Middle East like never before
![Climate Conviction at What Price?](https://reseuro.magzter.com/100x125/articles/9708/1724327/I0pJRJSkn1717696240028/CLIMATE-CONVICTION-AT-WHAT-PRICE.jpg)
Climate Conviction at What Price?
Fifty years ago experts doubted Americans would pay to save the environment. Only some of their fears are still true