IISc develops simple sensor for liver cancer detection

Researchers at the Indian Institute of Science (IISc), Bengaluru have developed a unique luminescent probe that uses terbium, a rare earth metal, to sense the presence of an enzyme called -glucuronidase, which can potentially aid in the detection of liver cancer.

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The roots of the project trace back nearly a decade, beginning with the team’s experiments on metal ions and their gel-forming properties. The team found that terbium ions couched in a gel matrix derived from bile salts can emit green fluorescence. Within the same gel matrix, the team added