In a study on intermittent fasting published in the prestigious journal JAMA Internal Medicine on September 28, 2020, researchers questioned, “What is the effect of time-restricted eating on weight loss and metabolic health in patients with overweight and obesity?” The researchers’ findings acknowledge, “In this prospective randomized clinical trial that included 116 adults with overweight or obesity, time-restricted eating was associated with a modest decrease (1.17%) in weight that was not significantly different from the decrease in the control group (0.75%).” Meaning that during the three-month study on a daily 16-hour-fast (eating all their meals between noon and 8:00 pm), participants only lost 2 to 3 pounds, slightly better than their control group. The most concerning finding of the study was that 65 percent of weight loss from the fasting group was not fat, but from lean body mass and muscle. A healthy weight loss comes from a diet that enhances body fat loss, not muscle and lean body mass. Having more muscle increases metabolism and helps you burn more calories over a 24-hour period.
A newer study published study in the March 2, 2021 Journal Cell Reports concluded that every other day fasting makes it more difficult to lose belly fat and deep visceral abdominal fat. Increasing abdominal fat is strongly linked to increased incidence of type 2 diabetes and cardiovascular disease.
This new study was done in mice and not humans, because their physiology is similar but mice have a much faster metabolism. This is important because it allowed the researchers to use advanced instrumentation, examining tissues and measuring changes carefully and more precisely in the body much more easily.
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