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I quit microdosing Ozempic and it's an enormous release
The Independent
|March 14, 2025
The new craze of using lower-than-recommended dosages of weight loss drugs to slim down might sound tempting, says Charlotte Cripps, but counting the clicks is no way to live

Is it 32 clicks? Or 37 clicks? I'm holding my Ozempic pen, a prefilled injection containing the active ingredient semaglutide, and trying to remember how many clicks I should listen out for when turning the pen dial to split my 1mg dose in half to 0.50mg. But then I realise I have no more needles left – each pen has four doses and I’m trying to get six doses out of it.
Damn! I could buy another new box of them online for next-day delivery. I’ve done it before. Or should I leave this dose in the fridge for a rainy day – and bring it out if an insatiable hunger returns and I start laying into a loaf of bread?
I’ve also been spacing out the 1mg dosages for a while, so instead of taking it weekly, as per the instructions, I take it every two weeks, or even three. It certainly saves money – a 1mg pen costs about £160 for four weeks – and it still seems to do the trick if I make it last for longer.

I have too many questions, and don’t want to be dependent on a drug forever. Is low-dose Ozempic a good way to maintain weight loss for the foreseeable future? Or else, I could just use it liberally, as and when needed. What happens if I stop? Should I wean myself off it?
It sounds insane – and it is. Welcome to the world of microdosing weight loss drugs. If I’d had this conversation with myself a few years ago, I would have sounded like I was from another planet but now it’s the new normal. I didn’t even know I was microdosing when I was playing around with doses of my own accord.
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