LONELY ANGIE'S EMPTY-NEST SYNDROME!

Lost & adrift as kids move on with their lives

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AGONIZED Angelina Jolie's grown-up kids are striking out on their own — and the mopey mom of six is nearing a nervous breakdown as she faces an impending empty nest, tipsters tell GLOBE.

Angie, 49, recently revealed that she gave her New York City apartment to one of her three sons — without naming names — and now the ritzy residence is a crash pad for the rest of her brood whenever they're in the Big Apple.

But the Maleficent movie witch recently warbled, “The other day, I said I was going to pop by, and he was like, ‘Can you just give me a day to clean?’”

While Angie appeared to make light of the remark, a source close to the scrawny star squeals she was “devastated” by the brush-off!