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Tobacco chewers with high-risk genes get oral cancer a decade earlier: Study
Hindustan Times Delhi
|November 30, 2025
THE STUDY HAS ANALYSED DNA OF 2,160 PEOPLE WITH BUCCAL MUCOSA CANCER AND 2,325 PEOPLE WITHOUT THE DISEASE
Tobacco chewers with multiple risky genetic variations develop oral cancer 10 to 20 years earlier than others who lack such genetic variations and chew similar amounts of tobacco, a study by the Centre for Cancer Epidemiology at the Tata Memorial Centre has revealed.
The research was published on Saturday in Lancet Discovery Science journal eBioMedicine. Researchers at the Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) analysed DNA of 2,160 patients with buccal mucosa cancer, which affects the inner cheek, and 2,325 people without the disease, across an 11-year period from 2010 to 2021 to understand why oral cancer strikes earlier in certain people.
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