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WHAT IS CHRONIC PAIN?

Prevention US

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November 2025

When you strain your back or burn your arm, receptor cells send messages along your nerve pathways to your brain. This results in a feeling of pain, a signal from your body that you must tend to it; when you get better, the pain should subside. But for an estimated one in five American adults, pain remains a constant companion.

WHAT IS CHRONIC PAIN?

Chronic pain is defined as pain that lasts at least three months, often persisting well after any original injury has resolved.

In some cases the pain comes on without a known cause. “Chronic pain is a physical and an emotional response not only to actual tissue damage but also to perceived tissue damage,” says Leena Mathew, M.D., a pain management specialist at Columbia University Medical Center.

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