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Manali Petro imposes safety mandates on distributors in wake of Coldrif cough syrup crisis
Chronicle Pharmabiz
|October 16, 2025
In a direct and stringent response to the health crisis triggered by contaminated Coldrif cough syrup which resulted in the death of at least 21 children, Manali Petrochemicals Limited (MPCL) in Chennai, a key player in India's solvent manufacturing sector, has issued sweeping new mandates for its propylene glycol IP (PG IP) product.
The move comes as the Indian pharmaceutical supply chain scrambles to restore confidence following the tragic incidents linked to diethylene glycol (DEG) contamination, a toxic substance that may be mistakenly substituted for or contaminate pharmaceutical-grade solvents.
As one of the three major domestic manufacturers of essential chemical intermediates, MPCL's guidelines are focused on ensuring the integrity of the crucial PG IP, a solvent widely used in pharmaceutical preparations like oral liquids. The company's official instruction sheet explicitly addresses distributors, dealers, and customers, indicating a zero-tolerance approach to quality control from factory gate to final use in manufacturing units. The core message is clear, every stage of the supply chain now requires forensic accountability.
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