DNA DATA STORAGE: Nature Provides A Way

Engineers have successfully been pushing more storage into smaller spaces for decades, but that can’t go on forever.

- Troy Dreier

The next big jump in data storage could take the form of the DNA inside all organic matter: Scientists in labs across the country are experimenting with synthetic DNA as a storage medium.

“If you look at where electronics is going, silicon technology, a lot of the basic technology that we use to build computers today, we’re approaching the limit in almost all of them,” says Luis Henrique Ceze, associate professor of computer science and engineering at the University of Washington. “DNA is very dense, it’s very durable, and it takes very little power to maintain, so there’s a lot of advantage of using DNA for data storage.”

Ceze has been working with Karin Strauss, a computer architecture researcher with Microsoft Research, on a collaboration between the two institutions—a project that bridges computer science and biology. For a team of roughly 20 people, the University provides the molecular biologists, and Microsoft provides the computer scientists.

To understand how DNA could be used for storage, consider that all computer data is binary, or base-2. DNA is base-4, composed of adenine, cytosine, guanine, and thymine (abbreviated as A, C, G, and T). The first step is converting base-2 information to base-4, so A corresponds to 00, C to 01, G to 10, and T to 11 (that simplifies it a bit but gets across the idea).

Then scientists use a machine called a DNA synthesizer to combine the four chemicals in the right order. The result stores the information many times over as a salt like cluster smaller than the tip of a pencil. Reading that information back requires a DNA sequencer.