Perlen Packaging Revolutionising Dry Powder Inhalation

Matteo Trisoglio, Manager Business Development, Perlen Converting, gives an insight on PERLAMED-BLIST, which has a simple design with low manufacturing cost

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SINCE THE invention of the multi dose, dry powder inhaler back in the 50s the API´s are administered in multi dose devices that are quite complex. This complexity requests patients to be skilled on their devices, not ideally for disposable and/or single use applications and, furthermore, requests high manufacturing costs. Perlen Packaging presented during the Pharma-Pack 2017, in Paris, the world’s first thermo-formed Inhaler (BLISTair).

Advantage of the products

The thermo-formed packaging is protecting the device itself throughout a high barrier film that Perlen is selling since years in the market with comparable barrier efficiency like Alu-Films that are in use for such applications. On one hand, the thermo-formed packaging is protecting the powder and at the same time, the packaging is the device itself.

The handling of this device is extremely intuitive, there is simply to pull a lash of the device to open up the powder chamber and inhale the API.

For this reason, for the first time, a disposable single use inhaler is available to the market, without a need for a secondary packaging. The primary packaging is already the device!

The fields of applications are extremely wide. The requests Perlen has since first presentations are so wide, it starts from asthma/COPD to vaccines, over to emergency and/or military applications as well as pain and cold treatments (OTC).

Obviously, the correct defined amount of inhalations, given by the nature of this system, allows running perfect clinical trials with a set number of inhalations. As well as an application dedicated to a fixed period of time, limited inhalation period (E.g. in hospitals) the 'BLISTair' find its market. Lung cancer applications, palliative medication pain cold and OTC could be ideally administered in the case of 'BLISTair.'