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Health experts call for more clinical trials to focus on new treatments for women

The Guardian

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May 07, 2025

Health experts are calling for more clinical trials to focus on finding new treatments for women as data reveals they are severely underrepresented, with 67% more male-only studies than female-only projects.

- Andrew Gregory

Details of thousands of studies were collected by the Medicines and Healthcare products Regulatory Agency (MHRA) and the University of Liverpool. The evidence shows the UK is a hub for pioneering research, with treatments such as gene therapies becoming a new growth area.

But a review of the data by the Guardian found women were significantly underrepresented. Both sexes were included in most trials (90%), but male-only trials (6.1%) were nearly twice as common as female-only studies (3.7%). Pregnant and breastfeeding women were especially underrepresented - involved in just 1.1% and 0.6% of trials respectively.

Women's health experts expressed alarm over the figures, which they said meant women and their doctors were having to make decisions about whether to take a drug in a "vacuum of evidence". Some areas of research were dominated by men at all levels - funders, researchers, consultants and patients - and as a result there could be a "reluctance" to fund female-only trials, the experts added.

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