Inflammation linked to frailty, social deprivation, heart disease risk in women

Chronic inflammation may be associated with an increased risk of frailty, social disadvantage, and cardiovascular disease (CVD), according to a study.

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The study, published in the journal Communications Medicine, looked at 74 inflammation-related proteins in blood samples from more than 2,000 women aged between 37 and 84 years and explored how inflammation was linked to frailty, area-level social deprivation, and CVD risk.

The researchers identified 10 inflammatory proteins that were associated with both frailty and living in a deprived area. Of these, four proteins involved in cellular signalling, growth, and movement (TNFSF14, HGF, CDCP1, and CCL11) were also linked to an increased risk of cardiovascular disease.