Cannabis and mental health

Understanding the endocannabinoid system is essential to understanding how cannabis may affect mental health, says Thomas Walker. Never self-medicate, but rather always consult a doctor first.

- Thomas Walker

For a while now, there’s been growing interest in the connection between cannabis and mental health.

Endocannabinoids, or body-produced cannabinoids, enzymes and receptors make up the complex network known as the endocannabinoid system (ECS), which controls a variety of physiological activities. It is essential for preserving homeostasis (stability) in the body.

The significance of the ECS increases when it comes to mental health. According to studies, the ECS helps to control mood, anxiety and stress reactions. It does this by controlling the release of neurotransmitters, which have a significant effect on mental and emotional states.

For example, depression can affect the working of the ECS. Restoring ECS balance may lessen symptoms of depression.

Cannabinoids from the cannabis plant, such as tetrahydrocannabinol (THC) and cannabidiol (CBD), can interact with the ECS by binding to cannabinoid receptors.

The psychoactive component of cannabis, THC, binds largely to cannabinoid 1 receptors. This causes intoxication and modifies mood and perception.

CBD interacts with the ECS in a more complicated way, altering receptor activation and boosting the body’s own endocannabinoids.

DEPRESSION AND ANXIETY