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Updated Covid-19 shot led to less severe illness in US in 2024: Study

The Straits Times

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October 10, 2025

The previous year's updated Covid-19 vaccines helped prevent severe outcomes including hospitalisations and deaths, according to data from a large study of US military veterans published on Oct 8.

Vaccinated veterans who developed Covid-19 after receiving the 2024-2025 boosters from Moderna or Pfizer/BioNTech were also less likely to visit the emergency room for complications, compared with unvaccinated Covid-19 patients, researchers reported in The New England Journal of Medicine (NEJM).

The researchers tracked 164,132 veterans who simultaneously received a 2024-2025 Covid-19 booster and a flu shot, and 131,839 who received only the flu vaccine.

The vast majority of participants were at least 45 years old, and virtually all who received a Covid-19 shot got one of the two approved mRNA-based vaccines that have faced renewed scrutiny from US Health Secretary Robert F. Kennedy Jr, who has questioned their safety and efficacy, contrary to scientific evidence.

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