Extracellular vesicles can treat defects, regenerate bones: ILS

IN a significant study, scientists at the Institute of Life Sciences (ILS), Bhubaneswar have discovered that critical-sized bone defects can be successfully treated with regeneration of bones by utilising extracellular vesicles found in body fluids.

- HEMANT KUMAR ROUT @Bhubaneswar

The researchers have got promising results during initial trials on mice models. Their discovery offers targeted treatment strategies and improved efficacy paving the way for more effective and less invasive therapies for patients with critical bone defects.

The bone defects arise due to various health conditions including surgery for osteosarcoma, which is a rare and aggressive bone cancer. In case of metastatic osteosarcoma, the tumour site is surgically removed resulting in a large cavity in the bone while in major bone fractures, part of the bone is completely or partially broken, causing pain and loss of functionality.