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COMMON MOLECULE OFFERS CLUE TO MAKING OLD MUSCLES YOUNG AGAIN
Southern Mail Newspaper
|June 17, 2025
Researchers found that five daily injections of prostaglandin E2 restored muscle stem cell function in aged mice
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As we age, it gets harder to recover from a fall, injury or even a tough workout because the body's muscle-repair system starts to falter. Muscle stem cells (MuSCs), the in-house repair crew, stop dividing and rebuilding tissue, losing their ability to respond to damage.
A study in Cell Stem Cell on June 12 suggested this decline may be reversible. The key isn't some futuristic therapy but a molecule already used in hospitals today.
Researchers found that five daily injections of prostaglandin E2 (PGE2), a compound involved in inflammation and used clinically to induce labour, restored muscle stem cell function in aged mice. After treatment, older mice regained the ability to regenerate damaged muscle: their muscle fibres grew larger, muscle mass increased, and strength improved by about 20% compared to their untreated peers.
Diese Geschichte stammt aus der June 17, 2025-Ausgabe von Southern Mail Newspaper.
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