Glasgow Univ's bioengineered bone marrow used in leukaemia research

UNIVERSITY of Glasgow rely used the first bioengineered bone marrow model to carry out vital cancer research, offering new insights into potential therapies for the disease.

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The breakthrough is documented in a new study, published in the journal Biomaterials, and represents an important step forward in being able to carry out medical research without the use of animals.

The study details the efficacy of CAR T-cell therapy - a promising new blood cancer treatment in targeting acute myeloid leukaemia (AML), the most common leukaemia in adults. Researchers say their new bioengineered model has been able to deliver the kind of human-relevant insights and information that current research methods that rely on animal models have so far been unable to achieve.