Proton Pump Inhibitors And Acid Reflux
Optimum Nutrition|Autumn 2017

This summer, a study published in the online journal BMJ Open 1 revealed that long-term use of commonly-prescribed proton pump inhibitors (PPIs) was associated with a higher risk of early death. Lisa Patient looks at what recent research says about both PPIs and acid reflux

Lisa Patient
Proton Pump Inhibitors And Acid Reflux

Sometimes prescribed for the treatment of gastric ulcers, bacterial infection Helicobacter pylori, and diseases such as Barrett’s oesophagus (a non-cancerous complication of chronic acid reflux that can develop into cancer in some people), PPIs are most commonly prescribed for acid reflux.

Known as gastro-oesophageal reflux disease (GORD); the symptoms of acid reflux include heartburn, an acid taste in the mouth, bad breath, bloating, nausea and/or vomiting. Whilst PPIs have been shown to be effective in treating the condition, recent studies indicate that long-term use may have serious consequences. For this reason, the team behind the latest research has urged caution over prescribing PPIs unnecessarily.

Researchers at the Washington University School of Medicine, USA, studied more than 250,000 medical records of people taking PPIs or H2 blockers. While PPIs inhibit the enzymes necessary for acid production in the stomach, reducing it to around 10 percent of normal acid production, H2 blockers reduce the amount of histamine (which stimulates acid production) released in the stomach. The team found that, compared with H2 blocker use, PPI use was associated with a 25 percent heightened risk of death from all causes — a risk that increased the longer PPIs were taken. 

Diese Geschichte stammt aus der Autumn 2017-Ausgabe von Optimum Nutrition.

Starten Sie Ihre 7-tägige kostenlose Testversion von Magzter GOLD, um auf Tausende kuratierte Premium-Storys sowie über 8.000 Zeitschriften und Zeitungen zuzugreifen.

Diese Geschichte stammt aus der Autumn 2017-Ausgabe von Optimum Nutrition.

Starten Sie Ihre 7-tägige kostenlose Testversion von Magzter GOLD, um auf Tausende kuratierte Premium-Storys sowie über 8.000 Zeitschriften und Zeitungen zuzugreifen.

WEITERE ARTIKEL AUS OPTIMUM NUTRITIONAlle anzeigen
Summer Of
Optimum Nutrition

Summer Of

Summer is when we want to be out and about, as the warm embrace of the sofa on a cold winter’s night becomes a distant memory. So where do you go when the brain is willing but the body just can’t cut it at the same level of performance that it managed decades ago? Graeme Wilcockson reviews a few ways to satisfy those competitive weekend instincts that will tax both mind and body — yet leave you able to move on Monday morning

time-read
7 Minuten  |
Summer 2016
Common Kitchen Practices Making Us Sick
Optimum Nutrition

Common Kitchen Practices Making Us Sick

Every year, thousands of us fall sick from food poisoning because of how we have handled food. Louise Scodie and Louise Wates look at common ways in which we are going wrong

time-read
6 Minuten  |
Summer 2017
Could Antioxidants Save Our Bacan?
Optimum Nutrition

Could Antioxidants Save Our Bacan?

Nitrates and nitrites have long been linked to cancer. We look at how they are part of a chain reaction that may not always be harmful to human health... So what’s the case with bacon?

time-read
7 Minuten  |
Spring 2018
Eat For A Glow That Is More Than Skin Deep
Optimum Nutrition

Eat For A Glow That Is More Than Skin Deep

Now that summer is here, it’s time to peel off the layers and make some vitamin D. But if your skin isn’t as peachy as you would like, or if you are worried about staying safe in the sun, find out how good nutrition may support your skin’s health. Maggie Charlesworth writes

time-read
10 Minuten  |
Summer 2018
Natural Beauty
Optimum Nutrition

Natural Beauty

If headlines about microbeads from cosmetics polluting our seas have got you wondering how you can do your bit for the environment, try using nature’s harvest to feed your skin. Hannah Maryse Robinson writes

time-read
2 Minuten  |
Summer 2018
A Summer Selection Of Goods And Goodies
Optimum Nutrition

A Summer Selection Of Goods And Goodies

Lazy Vegan frozen Chunky Pulled Peaz is a gluten-free, plant-based protein source suitable for vegans and — with a substantial texture — flexitarians.

time-read
2 Minuten  |
Summer 2019
Do Something Different
Optimum Nutrition

Do Something Different

As many of us are concerned about keeping our brains active, Ellie Smith investigates whether trying something completely new could boost both our brain health and mental wellbeing

time-read
5 Minuten  |
Summer 2019
Lifting Weights, Lifting Confidence
Optimum Nutrition

Lifting Weights, Lifting Confidence

When Bianca Mills was bullied at school she could not have dreamt that she would be able to speak in front of a group of women, let alone coach them in lifting free weights. She told Louise Wates why she believes buddying-up is just as important as physical strength for fostering confidence

time-read
8 Minuten  |
Summer 2019
Teaching Children How To Forage
Optimum Nutrition

Teaching Children How To Forage

Catherine Morgan finds out how foraging can teach children (and adults) about more than nature’s store cupboard, and can foster an understanding of and respect for the environment.

time-read
3 Minuten  |
Summer 2019
Keep Calm And Curry On
Optimum Nutrition

Keep Calm And Curry On

In August, India celebrates the anniversary of Indian Independence, yet the Anglo-Indian community, a legacy of the British Raj with its roots in European and Indian ancestry, still treads the cultural line between both communities. Jenny Mallin, author of A Grandmother’s Legacy, tells us about the fusion food in her family and recipes passed down through the generations

time-read
5 Minuten  |
Summer 2018