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LixiLan
Diabetes Health
|October / November 2017
Dr Rajesh Javherani discusses how the combination drug LixiLan helps improve glycaemic control.
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What is LixiLan?
LixiLan is an injectable drug which contains a fixed ratio combination of insulin glargine and lixisenatide, a glucagon-like peptide 1 (GLP-1) receptor agonist for the treatment of Type 2 Diabetes. It's given in the form of an injection similar to the modern delivery system of insulin (i.e. in the form of a pen). The drug is injected once a day, subcutaneously, preferably over the abdomen.
How it works
It is a single, once-daily injection to lower both fasting and postprandial blood glucose. Insulin glargine taken generally once a day serves as a basal or ‘background’ insulin. It stays in the body for 18 to 24 hours and is said to have little-to-no peak, providing steady blood sugar management throughout an 18 to 24 hour period.
Lixisenatide is a once-daily GLP-1 receptor agonist. A GLP-1 drug is a peptide that naturally occurs in the human body, released within minutes after eating a meal. It works to lower blood sugar levels by suppressing the natural glucagon secretion from the pancreatic alpha cells. It also stimulates insulin secretion by pancreatic beta cells.
Diese Geschichte stammt aus der October / November 2017-Ausgabe von Diabetes Health.
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