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Researchers find ways to minimise side effects of breast, ovarian cancer treatment
March 21, 2024
|The Daily Guardian
Certain anti-cancer medications also target healthy cells in addition to malignant cells.
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Their use may become restricted if their effects on the latter are excessively powerful. The mechanism of action of PARP inhibitors, which are specifically used for treating breast and ovarian cancer in individuals with the BRCA gene mutation, has been determined by a team from the University of Geneva (UNIGE) in cooperation with Basel-based FoRx Therapeutics. These inhibitors prevent the PARP proteins from engaging in two distinct functions. Healthy cells are protected while the harmful effect on cancer cells is maintained by inhibiting one of them.
The effectiveness of these treatments will be enhanced by this research, which was published in the journal Nature.
هذه القصة من طبعة March 21, 2024 من The Daily Guardian.
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