If We Can Eradicate Zombie Cells
Popular Mechanics US|July - August 2023
AS WE AGE, OUR BODIES FILL UP WITH a type of dysfunctional cell that permanently stops dividing, called a "senescent cell."
Monique Brouillette
If We Can Eradicate Zombie Cells

These "zombie cells" linger in our tissues, emit inflammatory signals, and increase the risk of age-related diseases. And just like zombies that spread their living-dead condition through a bite or scratch, senescent cells can damage their healthy counterparts through chemicals they emit.

When these cells were first discovered 60 years ago, scientists regarded senescence as a strange phenomenon. But in 2011 and again in 2016, a research group from the Mayo Clinic genetically engineered mice to have no senescent cells and showed that the mice did not develop cataracts or other signs of aging. The mice without senescent cells could increase their "healthspan," living disease-free into old age, according to Nathan LeBrasseur, PhD, a researcher who is studying senescent cells in the skeletal muscles of mice.

This story is from the July - August 2023 edition of Popular Mechanics US.

Start your 7-day Magzter GOLD free trial to access thousands of curated premium stories, and 8,500+ magazines and newspapers.

This story is from the July - August 2023 edition of Popular Mechanics US.

Start your 7-day Magzter GOLD free trial to access thousands of curated premium stories, and 8,500+ magazines and newspapers.

MORE STORIES FROM POPULAR MECHANICS USView All
The Cascading Failures Behind One of the Worst Building Collapses in U.S. History
Popular Mechanics US

The Cascading Failures Behind One of the Worst Building Collapses in U.S. History

Engineers are still investigating the collapse of Champlain Towers South in Surfside Florida, but early findings shed light on a risk facing poorly constructed residential and office buildings,

time-read
8 mins  |
March - April 2024
Cutting the Cord
Popular Mechanics US

Cutting the Cord

THE HANDHELD CIRCULAR SAW IS PERHAPS THE MOST VERSAtile power tool for cutting wood.

time-read
2 mins  |
March - April 2024
How Three Amateurs Solved the Zodiac Killer's '340' Cipher
Popular Mechanics US

How Three Amateurs Solved the Zodiac Killer's '340' Cipher

The mysterious code stumped the FBI and NSA for 53 years. What does the key, and the resulting solution, tell us about the infamous murderer?

time-read
10+ mins  |
March - April 2024
POPULAR MECHANICS TOP AWARDS 2024
Popular Mechanics US

POPULAR MECHANICS TOP AWARDS 2024

For more than 120 years, Popular Mechanics has been a heavy-duty brand. We see no reason to change that now.

time-read
6 mins  |
March - April 2024
How This Particle Could Break Our Understanding of Reality
Popular Mechanics US

How This Particle Could Break Our Understanding of Reality

EINSTEIN'S SPECIAL THEORY OF relativity teaches us that nothing can accelerate past the speed of light. But what if, when you were born, you were already moving faster than light? What would that look like?

time-read
3 mins  |
March - April 2024
The Right Way to Use a Fire Extinguisher
Popular Mechanics US

The Right Way to Use a Fire Extinguisher

A FIRE EXTINGUISHER IS MORE THAN A of one 5-gallon bucket becomes the size of 64 burning buckets. Just 180 seconds after it begins, a fire can be transformed from a nuisance to a room-size, life-threatening inferno.

time-read
2 mins  |
March - April 2024
How the World's Largest Spherical Structure Was Built
Popular Mechanics US

How the World's Largest Spherical Structure Was Built

THE SHINY, NEW LAS VEGAS SPHERE IS more than just a 17,600-seat amphitheaterstyle venue hosting a U2 residency. Since its opening in September 2023, it's become the world's largest spherical structure, at 516 feet wide and 366 feet tall.

time-read
2 mins  |
March - April 2024
The Army's Drone-Killing Laser Weapon
Popular Mechanics US

The Army's Drone-Killing Laser Weapon

THE U.S. ARMY FIELDED ITS FIRST LASERweapon-equipped unit in October. Based at Fort Sill, Oklahoma, the unit took possession of four laser-equipped Stryker infantry combat vehicles, each mounting a 50-kilowatt-class laser-weapon system. The combination of Stryker and laser can down both artillery, such as mortars and rockets, and drones in-flight.

time-read
3 mins  |
March - April 2024
Why It's So Hard to Mine the World's Largest Lithium Deposit
Popular Mechanics US

Why It's So Hard to Mine the World's Largest Lithium Deposit

A Pass, or Peehee Mu'huh to the local Paiute people has been mined since the 1970s, so the new analysis merely confirms what locals have long known about the area.

time-read
2 mins  |
March - April 2024
WHAT THE WORLD'S MOST POWERFUL X-RAY LASER WILL DO FOR SCIENCE
Popular Mechanics US

WHAT THE WORLD'S MOST POWERFUL X-RAY LASER WILL DO FOR SCIENCE

DEEP UNDER MENLO PARK, California, there is a threemile-long machine operating in a tunnel that scientists are keeping colder than even some of the deepest reaches of space.

time-read
3 mins  |
March - April 2024