Arsenal were their title rivals across the whole of last season and start today's match just a point behind City in the league table despite Pep Guardiola's side winning their first six out of seven matches.
The Blues won both of the encounters last season, which proved to be pivotal in them retaining the league title and going on to win a historic Treble.
Arsenal then spent big money to strengthen in the summer, recruiting the likes of Declan Rice and Kai Havertz, and Mikel Arteta will be hoping to provide an even stronger challenge this season.
City will be without the suspended Rodri and the injured John Stones, while the Gunners are waiting on the fitness of Bukayo Saka.
We've looked at the big talking points for the Emirates clash ...
CAN ARSENAL DELIVER?
Pep Guardiola said that even if his team had recorded a third straight defeat in midweek his confidence in them would not have faltered, and while the City manager can exaggerate in interviews this comment was dead right. City's reputation precedes them, meaning that it takes a lot more than a few defeats to raise question marks over the team.
Diese Geschichte stammt aus der October 08, 2023-Ausgabe von MEN on Sunday.
Starten Sie Ihre 7-tägige kostenlose Testversion von Magzter GOLD, um auf Tausende kuratierte Premium-Storys sowie über 8.000 Zeitschriften und Zeitungen zuzugreifen.
Bereits Abonnent ? Anmelden
Diese Geschichte stammt aus der October 08, 2023-Ausgabe von MEN on Sunday.
Starten Sie Ihre 7-tägige kostenlose Testversion von Magzter GOLD, um auf Tausende kuratierte Premium-Storys sowie über 8.000 Zeitschriften und Zeitungen zuzugreifen.
Bereits Abonnent? Anmelden
Turnout down for mayoral elections
ANDY BURNHAM and his mayoral Labour counterparts in West Yorkshire, South Yorkshire and Liverpool City Region were re-elected with thumping majorities last week and used their platforms to hammer under-fire Rishi Sunak.
The route of the problem
News on Metrolink expansion could be announced soon... but will Stockport finally get tram service - and where?
Staff's anger as home-working scheme is axed
STAFF at JD Sports' HQ say they have been left furious following an announcement of a full return to office working.
This week I found myself in line at the local foodbank
Struggle to get by for victim of 'appalling miscarriage of justice'
Grrrowth industry
Booming dog business set to expand
SOAP WARS
TV favourites will battle it out at Manchester awards night
'There's nothing left at the end of the month'
Plight of almost a quarter of a million people in Greater Manchester who are 'living in the red'
Birthday love for Corrie Sal
CORONATION Street star Vicky Myers shared her love for her co-star as she helped celebrate her 43rd birthday.
CHURCH'S PRAYERS ANSWERED
A CHURCH shaken to its foundations by motorway traffic is no longer on the road to ruin.
Rebuild talks as fire-ravaged leisure centre to be bulldozed
Staff redeployed to other sites after suspected arson attack