“This work has an actual meaningful impact on patients’ lives,” he tells me during our interview one Wednesday morning.
To the layperson, the work that Simranjit is referencing might be hard to understand. After all, when presented on a website, these things come across as clinical, with copy that hints more at the outcome than the process. Inevitably, with life-changing technologies like what Guardant Health offers, it’s essential to be well-funded — and there’s nothing investors love more than outcomes, I’m sure.
“Our Guardant 360 Liquid Biopsy involves identifying fragments of tumour DNA circulating in the bloodstream,” he offers helpfully when I ask him how exactly Guardant Health detects cancer cells with pinpoint accuracy. The tumour releases its DNA into the bloodstream when its cells die. “It’s similar to how a pregnant mother’s bloodstream carries DNA from the foetus, which can be tested for genetic conditions like Down Syndrome or Turner Syndrome.”
“Once we’ve detected these fragments, we use advanced technologies like AI and bioinformatics to make multiple copies of them and piece them together like a puzzle.” This, he explains, helps them determine which mutation is causing the patient’s cancer. “When we find it, we report it to the doctor, who can then use the information to guide the patient’s therapy — like a GPS.”
WHY IT WORKS
Before the advent of Guardant Health’s 360 Liquid Biopsy, doctors had to do invasive tissue biopsies, where they would physically extract tissue samples from the tumour site. However, this method had limitations, especially in advanced cancer patients with multiple metastatic tumour sites.
Diese Geschichte stammt aus der August 2023-Ausgabe von The PEAK Singapore.
Starten Sie Ihre 7-tägige kostenlose Testversion von Magzter GOLD, um auf Tausende kuratierte Premium-Storys sowie über 8.000 Zeitschriften und Zeitungen zuzugreifen.
Bereits Abonnent ? Anmelden
Diese Geschichte stammt aus der August 2023-Ausgabe von The PEAK Singapore.
Starten Sie Ihre 7-tägige kostenlose Testversion von Magzter GOLD, um auf Tausende kuratierte Premium-Storys sowie über 8.000 Zeitschriften und Zeitungen zuzugreifen.
Bereits Abonnent? Anmelden
A Sophisticated Bachelor Pad
In this two-storey apartment belonging to a finance in professional, designer Jerry Tan of Joey Khu ID created distinct arez ork and play.
Fringe Modalities
Poet, frontwoman, and shamanic healer ArunDitha Emmanuel returns to Singapore with renewed vigour to push the state-enforced boundaries of art.
Taking On Decolonisation
The annual Per°Form Open Academy of Arts and Activations by T:> Works this year tackles the complex subject of decolonisation with a line-up of artists from the global south.
Japan at Half-speed
A walking tour through the Kunisaki Peninsula in Kyushu is an invitation to appreciate thé country’s beauty ata snail's pace.
Truffle Sabotage
In the heart of Chianti, dark tales of the truffle trade, bacchanalian feasts, and sun salutations await at Christina Ong's COMO Castello del Nero in Tuscany.
Is Barolo the Next Burgundy?
With Burgundy prices reaching starry heights, we find out why Barolo is the next frontier for oenophiles.
Hungry for Hansik
Hansik, or Korean food, is becoming more popular worldwide due to the proliferation of Korean pop culture. We explore two of the cuisine's stalwart elements.
Maxed Out
We explore the intricacies of high-performance tyre development inside Continental’s top-tier test facility in Germany and put its new MaxContact MC7 tyres to the test.
India Rising
From a culture whose glorious traditions have greatly influenced luxury jewellery today, young designers like Renu Oberoi are rewriting the narrative.
A Life Less Ordinary
Street culture pioneer-entrepreneur Feroze McLeod defies convention, even in his watch collection.
