“I hope I am not too old to take it up seriously nor too stupid about machines to qualify as a commercial pilot.”
—“Samuel Beckett,” by Deirdre Bair.
Gray bleak final afternoon ladies and gentlemen this is your captain your cap welcoming you aboard the continuation of Flyways flight 185 from nothingness to New York’s Laguardia non non non non non non nonstop to Chicago’s Ohare and on from there in the passing of gray afternoons to empty bleak eternal nothingness again with the Carey bus the credit-card machine the Friskem metal detector the boarding pass the in-flight magazine all returned to tiny bits of grit blowing across the steppe for ever
(Pause)
Cruising along nicely now.
(Pause)
Yes cruising along very nicely indeed if I do say so myself.
(Long pause)
This story is from the August 19, 2024 edition of The New Yorker.
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This story is from the August 19, 2024 edition of The New Yorker.
Start your 7-day Magzter GOLD free trial to access thousands of curated premium stories, and 9,000+ magazines and newspapers.
Already a subscriber? Sign In
Drug of Choice - The natural world contains many billions of potential medications. The question is how to find the ones that work.
AI. is transforming the way medicines are made. Bacteria produce numerous molecules that could become medicines, but most of them aren’t easily identified or synthesized with the technology that exists today. A small percentage of them, however, can be constructed by following instructions in the bacteria’s DNA. Burian helped me search the sequence for genes that looked familiar enough to be understandable but unfamiliar enough to produce novel compounds. We settled on a string of DNA that coded for seven linked amino acids, the same number found in vancomycin. Then Burian introduced me to Robert Boer, a synthetic chemist who would help me conjure our drug candidate.
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