India has over 1900 AI startups including biotechnology (Zinnov-NASSCOM India Tech Start-up Landscape Report 2022). The pharma industry will be a major beneficiary of AI’s applications and might spend around $3 billion on AI in drug discovery by 2025.
In the biotech sector, AI has a big role to play in the analysis, learning, prediction and better decisionmaking of innovative solutions in areas of agriculture. It includes crop harvesting, monitoring crop and soil, gene editing, forecasting plausible yield), health (such as medical data analysis for finding novel drug targets, forecasting drug efficacy and toxicity, speed up the drug development process, creating personalised medicine, medication management, detecting abnormalities like cancerous tumours, to build new wearable devices that can detect and monitor certain disorders), to modify the genes and traits of animals and create mixed or cross-breed versions, to provide efficient production and better product quality, to identify the locations of genes, classification of protein along with protein’s catalytic role & biological function, analysis of gene expression and predictive modelling.
This story is from the BioSpectrum Asia Feb 2024 edition of BioSpectrum Asia.
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This story is from the BioSpectrum Asia Feb 2024 edition of BioSpectrum Asia.
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New South Wales government injects $5M for critical research to address Silicosis crisis
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Singapore approves new asthma indication for GSK's Trelegy Ellipta
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What's APAC's Recipe of Success in CLINICAL TRIALS MARKET?
Asia-Pacific APAC) is emerging as one of the most promising and resilient markets for clinical trials. According to a report by Clinical Trials Arena, between 2017 and 2022, the region posted growth in clinical trials of around 10 per cent, outstripping growth in other major regions including the US, Europe and the rest of the world RoW). Asia’s growth far exceeded the overall average figure of 5.3 per cent per year. As of 2023, the number of trials reached 14,346 in APAC. Let's delve into the thriving clinical research landscape in the region and explore the trends driving its growth.
From Haematologic to Autoimmune DiseaseThe CAR-T Therapy Second Revolution
Cell and gene therapies have revolutionised the field of medicine, offering new treatment options for patients with various diseases that, by type of disease or severity, were considered untreatable until a few years ago. Rapid technological advancements in genetic and biological engineering and improvements in the quality and standardisation of the manufacturing process are fostering a marked increase in clinical development of these advanced therapies, generally named cell and gene therapies CGT), and they are expected to receive more approvals in the near future.
"Biotech startups still need support in terms of talent, and resources to bring their innovations to market"
Raymond Chow has recently stepped in as the Vice President, Asia Pacific at USheadquartered Cytiva, a global provider of technologies and services for biological therapies, formerly known as GE Healthcare Life Sciences.
"We are exploring opportunities to collaborate with startups and incubators"
Agilent Technologies, a global leader in analytical and clinical laboratory technologies, has named Padraig McDonnell CEO-elect and Chief Operating Officer (COO), succeeding current President and CEO Mike McMullen.
"Australia offers a simple, supportive and robust regulatory process to initiate human trials efficiently"
US-based Uvax Bio, LLC, a spin-off vaccine company from Scripps Research, employs proprietary 1c-SApNP platform technology invented by Dr Jiang Zhu of Scripps Research to develop and commercialise prophylactic vaccines for challenging infectious diseases.
"Regulatory encouragement of advanced tech, including AI will accelerate clinical trials in APAC"
Lokavant Holdings, a US-based clinical trial intelligence technology company provides clinical trial intelligence that enables study teams to make data-driven decisions, as well as risk-based quality management and monitoring services to pharmaceutical companies and contract research organisations (CROs).
What Are the Main Challenges of Modern Clinical Trials?
With a cumulative total of almost 478,000 globally registered trials from the year 2000 to 2023, and growing at around 10 per cent a year in the last five years, the pharmaceutical industry continues to invest in clinical trials as the gold-standard test of therapeutic safety and efficacy. In addition, as the world’s economies and populations move in new directions, the share of non-US trials has reached 54 per cent, a trend that is likely to continue, driven by demographics and epidemiology. As the pace accelerates, trial managers and clinicians face a significant challenge: the explosive growth of data volumes. To succeed in the future, clinical trials need to increase efficiency and better utilise clinical trial data to support informed clinical and operational decision-making.
How APAC Has Turned into Clinical Trial Behemoth
From being a consistent participant in clinical trial conduct worldwide, the APAC has emerged as a major power. A number of causes, including the region's thriving drug development innovation and the ongoing presence of international pharmaceutical corporations conducting multiregional studies, are driving this growth.
