In 1946, a doctor flew between Boston and Venezuela, a journey that took 14 hours. He suffered a deep vein thrombosis and decided that the long flight was the cause. Around the same time, a higher than expected incidence of clots was noticed in people sleeping in deckchairs in the London Underground during the Blitz. So the phenomenon of clots forming during immobility – especially when immobile in the sitting position – and the link between long flights and thrombosis has long been recognised. Why is there this association?
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