“You could administer antibody treatments to people who are infected, and it would reduce the disease burden.”
What is a spike protein and what is its function?
Daniel Wrapp A spike protein is a protein that decorates the surface of a coronavirus. Its job is to attach that virus to a host cell by binding to a receptor [on the host cell’s surface]. Once it’s attached, it fuses the viral membrane with the host cell membrane so that the virus can enter into the host cell and begin the process of replication. The spike protein is the main machine that the virus uses to enter into our cells. So, without the spike functioning properly on the surface of a virus, the virus is neutralised and is noninfectious.
Why did you focus on llamas?
Camelids, which is a family that includes camels, llamas, alpacas and a couple of other animals, produce this special class of small antibodies [proteins produced by the immune system to fight off harmful bacteria and viruses], which are sometimes called nanobodies. Camelid antibodies are about half the size of the conventional antibodies that you or I would produce, and because of that small size, they have enhanced stability and they’re also capable of binding to small crevices or pockets that larger antibodies wouldn’t otherwise be able to bind to. [This is why the llama antibodies can bind to the spike proteins on coronaviruses.]
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टीके (वैक्सीन) किस तरह काम करते हैं?
प्रतिरक्षा तंत्र हमारे शरीर में बीमारियों के खिलाफ सुरक्षा की व्यवस्था है। यह तंत्र अंगों, कोशिकाओं और प्रोटीन्स से मिलकर बना है जो साथ-साथ काम करते हैं और शरीर में बाहर से आने वाले घुसपैठियों पर नज़र रखते हैं, उन्हें नष्ट करते हैं। इन घुसपैठियों को रोगजनक (पैथोजेन) कहते हैं। इनमें बैक्टीरिया और वायरस शामिल हैं।
दावा: डेंगू से ठीक हो चुके लोग कोरोना से सुरक्षित
एशिया-अफ्रीकी देशों पर शोध में खुलासा, डेंगू से पैदा हुई एंटीबॉडी से मृत्युदर भी कम
दिल्ली में दूसरा सीरो सर्वे मे 29 फीसदी लोगों में मिले एंटीबॉडी
पिछले सर्वे के मुकाबले छह फीसदी है ज्यादा
पुणे में 51.5 प्रतिशत नमूनों में कोविड-19 से लड़ने के लिए एंटीबॉडी मौजूद: सीरो सर्वेक्षण
महाराष्ट्र के पुणे शहर में कोरोना वायरस से सबसे अधिक प्रभावित पांच वार्डों के 1,644 लोगों पर किए गए सीरो सर्वेक्षण के मुताबिक 51.5 प्रतिशित नमूनों में सार्स-कोव- 2 के संक्रमण से लड़ने में सक्षम एंटीबॉडी मिले हैं।
राहत: एंटीबॉडी बन जाने के बाद दोबारा संक्रमण का खतरा नहीं
• वैज्ञानिकों ने पहली बार की पुष्टि • कब तक कारगर रहेंगी, अभी स्पष्ट नहीं
अमेरिकी वैज्ञानिक का दावा, ढूंढ़ लिया जानलेवा कोरोना वायरस का इलाज
परीक्षण सफल होने के बाद सरकारी एजेंसी के पास इसे मंजूरी के लिए भेजा जाएगा