50% Covaxin Efficacy May Not Be As Bad As It Seems
The Times of India Delhi|November 25, 2021
Those Tested Had Greater Exposure During 2nd Wave Peak
Durgesh Nandan Jha

New Delhi: A study conducted by AIIMS has shown that two doses of Covaxin, the indigenous vaccine developed by Indian Council of Medical Research in collaboration with Bharat Biotech, is 50% effective in preventing symptomatic infection due to Covid-19. This is lower than the 77.8% efficacy claimed by Bharat Biotech after phase 3 trials of the vaccine.

However, there’s a caveat for the differing efficacy figures. The phase 3 trials looked at vaccine effectiveness in the general population, while the AIIMS study involved doctors, nurses and healthcare workers who were working in the hospital setting and, therefore, had a greater exposure to the coronavirus. Also, the study was conducted between April 15 and May 15, when the second Covid wave was at its peak in India and nearly 80% of the infection was caused by the Delta variant, which is known to have a higher rate of breakthrough infections compared with the other variants.

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