At 6am, 11 premises were searched in Greater Manchester, Cheshire and Staffordshire.
The strikes were the culmination of months of covert investigations.
Operation Ceramic hopes to smash the supply of class A and B drugs by organised crime gangs across the North West and Midlands.
GMP’s Serious Organised Crime Unit were backed by officers from the force’s City of Manchester district, the National Crime Agency, Cheshire Constabulary, and West Midlands Regional Organised Crime Unit.
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