Lose Fat and Boost TESTOSTREONE
Muscular Development|June 2021
Every bodybuilder or athlete understands too much body fat can be detrimental. For the bodybuilder, too much body fat detracts from the physique. The athlete can’t carry too much body fat because it decreases speed and quickness, thus diminishing athletic performance. Although fat tissue can be physically unappealing to the bodybuilder while negatively influencing athletic prowess, fat cells also perform an additional function that can negatively impact the athlete and bodybuilder by drastically decreasing the production of the muscle-building hormone testosterone.
Michael J. Rudolph

Fat tissue, in addition to storing energy in the form of triglycerides, can be considered an atypical endocrine organ given its ability to secrete several different hormones, known as adipokines, into the bloodstream. The most well-characterized adipokine, leptin, is secreted by fat cells after fat cells accumulate triglyceride. Essentially, the more body fat you have the greater the amount of leptin you have circulating in your blood. Leptin is a signal to the brain that decreases appetite and food intake while simultaneously stimulating the rate of fatty-acid oxidation, converting stored fat into energy. Unfortunately, leptin’s ability to decrease food consumption while burning fat can be offset by calorically dense foods – leading to increased body fat.

Since leptin is produced at concentrations that parallel the amount of fat reserves, individuals with greater body fat typically have greater levels of circulating leptin. Interestingly, many lines of clinical evidence show that greater body fat, along with correspondingly higher levels of leptin, is frequently associated with low testosterone levels in men. These observations indicate a potential connection between adipokines, such as leptin, and lower testosterone production.

Decreased Testosterone Production

Intriguingly, several relevant studies demonstrate leptin’s ability to reduce testosterone production. A study by Caprio et al.1 demonstrated in isolated testicular cells given an excessive amount of leptin, mimicking greater body fat, appreciably decreased testosterone production. Furthermore, in a study by Caprio et al.2, rats treated with leptin exhibited a diminished response to human chorionic gonadotropin (hCG) stimulated testosterone production. Given that hCG mimics the function of the natural testosterone stimulating substance known as luteinizing hormone (LH), this result implies that leptin is inhibiting the ability of LH to stimulate testosterone production.

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