Phase 3 trial of first home-grown drug for Alzheimer's begins
Business Standard|November 18, 2022
Now an Indian company working on the country's first home-grown, potentially affordable Alzheimer's drug Masupirdine (formerly SUVN 502) is raising hopes for 6.1 million senior citizens in India suffering from dementia.
SOHINI DAS
Phase 3 trial of first home-grown drug for Alzheimer's begins

Hyderabad-based Suven Life Sciences (Suven) has started recruiting patients for the Phase 3 trial of this novel drug that could possibly slow cognitive decline.

The company's stock surged nearly 9 per cent during the day's trade on the BSE.

Alzheimer's is a progressive neurological, degenerative disorder that causes the brain to shrink and the brain cells to die. According to a 2021 Lancet study on the burden of neurological disorders in India's states, Alzheimer's has claimed 129,000 lives in the country in 2019. About 3.7 per cent, or 6.1 million, senior citizens suffer from dementia.

This number is expected to treble by 2050, warns Jasrita Dhir, head-marketing and communications, Antara Senior Living.

Suven said on Wednesday it has started randomisation of the first patient in the Phase 3 global clinical trial of its drug Masupirdine for the treatment of agitation in patients with dementia of the Alzheimer's type. Clinical trial randomisation is the process of assigning patients by chance to groups that receive different treatments.

It is a multi-centre, randomised, double-blind, placebo-controlled study planned across 50 cities in North America and Europe.

"The study will enrol approximately 375 patients who will be randomised in a 1:1:1 to receive.

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