The young Sale scrum-half has been handed his chance to show just why he is one of the most highly-rated English No.9s in the game during the opening few weeks of the Gallagher Premiership with the World Cup winner away on international duty.
However, the Sharks are anxiously waiting for the results of a scan on a hip flexor injury De Klerk initially suffered during the Lions series. If it needs surgery, he could be out for months.
And with Will Cliff also injured, that potentially puts 20-year-old Quirke in line for a long run in the side. It has been a meteoric rise for the Chorlton lad, who only made his first-team debut in February as a substitute and has started just three games but has already shown enough to have been called up to England’s training camp for the Autumn internationals.
But the former Broughton Park junior and St Ambrose College pupil has been learning from the best on the way.
“I am missing Faf a bit now! He has been away quite a while,” Quirke told M.E.N. Sport.
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