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Ozempic maker's shares drop after Alzheimer's trials fail
The Guardian
|November 25, 2025
Novo Nordisk shares slumped yesterday after the drugmaker said the pill version of Ozempic had failed to slow the progression of Alzheimer’s disease in two large studies.
The Danish firm said patients who had taken the drug did not see their disease progress more slowly, dashing hopes for a new use for the blockbuster diabetes drug.
Shares in Novo, which are listed in Copenhagen, dropped by more than 10% in early trading yesterday before easing back to close about 5.5% down.
The company has grown to be one of the biggest in Europe after the success of its semaglutide-based drugs, Ozempic and the weight-loss jab Wegovy. But it has lost more than half its value this year amid concerns that it cannot win back its early lead in the market.
Studies had previously suggested the rate of dementia was lower in people with type 2 diabetes who take drugs such as semaglutide, compared with those given a placebo.
This story is from the November 25, 2025 edition of The Guardian.
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