Charles's pre-recorded audio - his first public words since Kate revealed she was undergoing chemotherapy - will be broadcast at a Royal Maundy service in Worcester Cathedral today.
He will say how Jesus set an "example of how we should serve and care for each other", and how as a nation "we need and benefit greatly from those who extend the hand of friendship to us, especially in a time of need".
While the King does not directly refer to his and his daughterin-law's health, his words will be interpreted as reflecting on the nation's response to his and Kate's challenges as they continue treatment for cancer.
The princess released an emotional video message last Friday revealing she has started a course of "preventative chemotherapy".
She later was said to be "extremely moved" by the public support following her announcement.
Kate faced mounting online conspiracy theories about her whereabouts and her condition after retreating from public view to recuperate following major abdominal surgery in January.
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